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CENPA Mouse anti-Human, Clone: 5A7-2E11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527710
DescriptionCentromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
|PBS with 50% glycerol and 0.09% sodium azide; pH 7.4|
|CENP A, cenpa, Centromere auto antigen A, Histone H3 like centromeric protein A|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Synthetic peptide corresponding to a portion of human CENP-A|
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