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CENPJ Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550377

Catalog No. PA550377


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Description

Description

The antibody detects endogenous levels of total CENPJ protein.

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintece of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.
Specifications

Specifications

CENPJ
Polyclonal
Unconjugated
CENPJ
Liquid
CENPJ
Fusion protein corresponding to residues near the C terminal of human centromere protein J
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.8 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9HC77
CPAP, LAP, LIP1
Rabbit
IgG
100 μL
-20°C
Primary
55835
Documents
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