CENPO Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 206111AP
DescriptionAccurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|CENP O, CENPO, centromere protein O, ICEN36, MCM21R|
|52504, 684439, 79172|
|CENPO Fusion Protein Ag14619|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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