Centrin 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 158771AP
DescriptionThe EF-hand type Ca2+-binding proteins family consists of several members, including Centrin-1, Centrin-2 and Centrin-3. The Centrin proteins are ubiquitously expressed cytoskeletal components that show increased expression during cell differentiation. Tissues where cilia are present, such as the retina and testis, express both Centrin-1 and -2, but Centrin-2 is also expressed in nondifferentiated, nonciliated retinal cells (retinoblastoma cells), liver, skeletal muscle and cardiac muscle. In these tissues, Centrin associates with the centrosomes, mitotic spindle poles and basal bodies. Knockdown studies reveal a requirement for Centrin in centriole duplication and organization of spindle pole morphology and the completion of cytokinesis. Centrin-3 plays a role in centrosome reproduction.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|CALT, Caltractin isoform 1, CEN2, Centrin 2, centrin 2,centrin2, centrin, EF hand protein, 2, CETN2|
|1069, 26370, 84593|
|Immunohistochemistry (Paraffin), Western Blot|
|Centrin 2 Fusion Protein Ag8638|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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