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  8. CGP 52411, Tocris Bioscience™

CGP 52411, Tocris Bioscience™

Catalog Number 336010
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
145915-58-8
C20H15N3O2
329.36
MFCD00236442
AAALVYBICLMAMA-UHFFFAOYSA-N
daph, 4,5-dianilinophthalimide, 5,6-bis phenylamino-1h-isoindole-1,3 2h-dione, 5,6-dianilino-1h-isoindole-1,3 2h-dione, unii-z13d008fz2, d03qtp, daph-1, 4,5-bis anilino phthalimide, 4,5-bis-anilino phthalimide, 1h-isoindole-1,3 2h-dione, 5,6-bis phenylamino
1697
CHEBI:53110
5,6-bis(phenylamino)-2,3-dihydro-1H-isoindole-1,3-dione
O=C1NC(=O)C2=CC(NC3=CC=CC=C3)=C(NC3=CC=CC=C3)C=C12
This item is not returnable. View return policy
145915-58-8
C20H15N3O2
329.36
MFCD00236442
AAALVYBICLMAMA-UHFFFAOYSA-N
daph, 4,5-dianilinophthalimide, 5,6-bis phenylamino-1h-isoindole-1,3 2h-dione, 5,6-dianilino-1h-isoindole-1,3 2h-dione, unii-z13d008fz2, d03qtp, daph-1, 4,5-bis anilino phthalimide, 4,5-bis-anilino phthalimide, 1h-isoindole-1,3 2h-dione, 5,6-bis phenylamino
1697
CHEBI:53110
5,6-bis(phenylamino)-2,3-dihydro-1H-isoindole-1,3-dione
O=C1NC(=O)C2=CC(NC3=CC=CC=C3)=C(NC3=CC=CC=C3)C=C12

Description

EGFR inhibitor. Also inhibits Aβ42 fibril formation

Selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). Also inhibits and reverses the formation of Aβ42 fibers associated with Alzheimer's disease. Eliminates calcium influx potential when coincubated with amyloid β-peptide (1-42) (Cat.No. 1428); reduces neurotoxicity by blocking Ca2+ influx into neuronal cells.
Quantity 10 mg
Formula Weight 329.35
Percent Purity >99%
Chemical Name or Material CGP 52411

Safety and Handling

Recommended Storage Store at Room Temperature
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