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  7. CGP 55845 hydrochloride, Tocris Bioscience™

CGP 55845 hydrochloride, Tocris Bioscience™

Catalog Number p-4783335
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
149184-22-5
C18H23Cl3NO3P
438.71
PXQAIXBYWZBYKJ-LINSIKMZSA-N
cgp 55845 hydrochloride, c18h22cl2no3p.hcl, cgp 55845a hydrochloride, s-r*,r*-isomer, 3-1-s-3,4-dichlorophenyl-ethyl amino 2-s-hydroxypropyl-phenylmethyl-phosphinic acid hydrochloride, phosphinic acid, 2s-3-1s-1-3,4-dichlorophenyl ethyl amino-2-hydroxypropyl phenylmethyl-, hydrochloride
9954841
benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid;hydrochloride
CC(C1=CC(=C(C=C1)Cl)Cl)NCC(CP(=O)(CC2=CC=CC=C2)O)O.Cl
This item is not returnable. View return policy
149184-22-5
C18H23Cl3NO3P
438.71
PXQAIXBYWZBYKJ-LINSIKMZSA-N
cgp 55845 hydrochloride, c18h22cl2no3p.hcl, cgp 55845a hydrochloride, s-r*,r*-isomer, 3-1-s-3,4-dichlorophenyl-ethyl amino 2-s-hydroxypropyl-phenylmethyl-phosphinic acid hydrochloride, phosphinic acid, 2s-3-1s-1-3,4-dichlorophenyl ethyl amino-2-hydroxypropyl phenylmethyl-, hydrochloride
9954841
benzyl-[(2S)-3-[[(1S)-1-(3,4-dichlorophenyl)ethyl]amino]-2-hydroxypropyl]phosphinic acid;hydrochloride
CC(C1=CC(=C(C=C1)Cl)Cl)NCC(CP(=O)(CC2=CC=CC=C2)O)O.Cl

Description

Potent and selective GABAB antagonist

Potent, selective GABAB receptor antagonist (IC50 = 5 nM) that prevents agonist binding (pKi = 8.35) and inhibits GABA and glutamate release (pEC50 values are 8.08 and 7.85 respectively). Inhibits GABAB responses to baclofen (IC50 = 130 nM in an isoproterenol assay) and potentiates the hypoglycemic response to glucose in vitro.
Quantity 10 mg
Formula Weight 438.71
Percent Purity >98%
Chemical Name or Material CGP 55845 hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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