Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Azoles
  7. Pyrazoles
  8. CGP 57380, Tocris Bioscience™

CGP 57380, Tocris Bioscience™

Catalog Number 27311
Click to view available options
Quantity:
1 mg
10 mg
50 mg
This item is not returnable. View return policy
522629-08-9
C11H9FN6
244.233
UQPMANVRZYYQMD-UHFFFAOYSA-N
mnk1 inhibitor, n3-4-fluorophenyl-1h-pyrazolo 3,4-d pyrimidine-3,4-diamine, 4-amino-5-4-fluoroanilino-pyrazolo 3,4-d pyrimidine, d0a7fq, cgp hplc, n-4-fluorophenyl-3h-pyrazolo 3,4-d pyrimidine-3,4-diamine, 3-n-4-fluorophenyl-1h-pyrazolo 3,4-d pyrimidine-3,4-diamine, 3-n-4-fluorophenyl-2h-pyrazolo 3,4-d pyrimidine-3,4-diamine, n3-4-fluorophenyl-1h-pyrazolo-3,4-d pyrimidine-3,4-diamine, n3-4-fluorophenyl-2h-pyrazolo 3,4-d pyrimidine-3,4-diamine
11644425
3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
This item is not returnable. View return policy
522629-08-9
C11H9FN6
244.233
UQPMANVRZYYQMD-UHFFFAOYSA-N
mnk1 inhibitor, n3-4-fluorophenyl-1h-pyrazolo 3,4-d pyrimidine-3,4-diamine, 4-amino-5-4-fluoroanilino-pyrazolo 3,4-d pyrimidine, d0a7fq, cgp hplc, n-4-fluorophenyl-3h-pyrazolo 3,4-d pyrimidine-3,4-diamine, 3-n-4-fluorophenyl-1h-pyrazolo 3,4-d pyrimidine-3,4-diamine, 3-n-4-fluorophenyl-2h-pyrazolo 3,4-d pyrimidine-3,4-diamine, n3-4-fluorophenyl-1h-pyrazolo-3,4-d pyrimidine-3,4-diamine, n3-4-fluorophenyl-2h-pyrazolo 3,4-d pyrimidine-3,4-diamine
11644425
3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F

Description

Selective inhibitor of Mnk1

Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC50 = 2.2 μM) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC50 = 3 μM) and inhibits LPS-induced TNFα expression in macrophages.
Quantity 1 mg
Formula Weight 244.23
Percent Purity >98%
Chemical Name or Material CGP 57380

Safety and Handling

Recommended Storage Store at +4°C
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit