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CGREF1 Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549320

Catalog No. PA549320


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Description

Description

CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.
Specifications

Specifications

Cgref1
Polyclonal
PBS with 0.09% sodium azide
P97586
Cell growth regulator with EF hand domain protein 1, Cell growth regulatory gene 11 protein, Hydrophobestin, Cgref1, Cgr11
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
245918
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Cgref1
Liquid
CGREF1
KLH conjugated synthetic peptide between 220-248 amino acids from the C-terminal region of rat Cgref1.
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Rat
Documents
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