CHD3 Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™

Mouse Recombinant Monoclonal Antibody

Supplier:  Active Motif 91273

Catalog No. 50-199-3793

Description

This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Specifications

• Antigen: CHD3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CHD3
• Gene Alias: 2600010P09Rik; AF020312; ATP-dependent helicase CHD3; CHD3; CHD-3; Chd7; chromodomain helicase DNA binding protein 3; Chromodomain-helicase-DNA-binding protein 3; hZFH; MGC40857; Mi 2a; Mi2 ALPHA; Mi-2 alpha; Mi-2 autoantigen 240 kDa protein; Mi-2a; Mi2-alpha; Prp7; Prp9 1; Prp9-1; ZFH; Zinc finger helicase; zinc-finger helicase (Snf2-like)
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 40111
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
• Gene Accession No.: O16102
• Gene Symbols: CHD3
• Immunogen: This antibody was raised against a synthetic peptide corresponding to amino acid residues 865-885 of Drosophila.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Drosophila
• Product Type: Antibody
• Isotype: IgG2a