Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CHIA Mouse anti-Human, Clone: OTI3H4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527414

Catalog No. PIMA527414


Add to cart

Description

Description

Chitinases are ubiquitous chitin-fragmenting hydrolases. The chitinase Chitotriosidase is capable of cleaving natural chitin and chitin-like substrates in humans and may play a role in immunity against pathogens containing chitin. Activated human macrophages secrete chitotriosidase, and increased plasma levels of chitotriosidase are a feature of patients suffering from Gaucher ft.s disease. Expression of mouse Chitotriosidase is restricted to brain, skin, bone marrow, kidney, tongue, stomach and testis. The homology between chitotriosidase and chitinases found in lower organisms is significant. Acidic mammalian chitinase precursor (AMCase) degrades chitotriose and chitin. AMCase is highly expressed in stomach tissues and is primarily a secreted protein. It is involved in Th2-mediated inflammation and may play a role in asthma and allergic diseases.
Specifications

Specifications

CHIA
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9BZP6
AMCASE, CHIT2, TSA1902, acidic mammalian chitinase, lung-specific protein TSA1902
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
27159
Immunohistochemistry (Paraffin), Western Blot
OTI3H4
Unconjugated
CHIA
Liquid
CHIA
Full length human recombit protein of CHIA produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit