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CHM Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549272

Catalog No. PA549272

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predomit pathway for Rab protein geranylgeranylation.
Specifications

Specifications

CHM
Polyclonal
PBS with 0.09% sodium azide
P24386
Rab proteins geranylgeranyltransferase component A 1, Choroideremia protein, Rab escort protein 1, REP-1, TCD protein, CHM, REP1, TCD
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1121
Western Blot
Unconjugated
CHM
Liquid
CHM
KLH conjugated synthetic peptide between 292-320 amino acids from the Central region of human CHM.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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