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CHN2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 182591AP

Catalog No. 50-173-2075


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Description

Description

This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specifications

Specifications

CHN2
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P52757, Q80XD1
ARHGAP3, Beta chimaerin, Beta chimerin, chimerin (chimaerin) 2, CHN2, RHOGAP3
Rabbit
IgG
150 μL
-20°C
Primary
1124, 69993
Western Blot
Unconjugated
CHN2
Liquid
Chn2
CHN2 Fusion Protein Ag13106
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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