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BioVision IncSupplier Diversity Partner Cholesterol Detection Kit (cell-based): Cholesterol Detection Kit (cell-based): Simple histochemical method of identification of unesterified cholesterol in a variety of cells. 100 assays. DFS Item

Manufacturer:  BioVision IncSupplier Diversity Partner K587100

Cholesterol is an essential structural component of animal cell membranes. It is required to maintain membrane structural integrity and fluidity. Cholesterol also serves as a precursor for the biosynthesis of several hormones, bile acid and vitamin D. Plasma membrane contains majority of the cellular cholesterol (80-90%) whereas little cholesterol resides in endoplasmic reticulum and in mitochondrial membrane. Transport of intracellular cholesterol within the cells to different compartments is through vesicular and non-vesicular pathways. Defects in these transport processes can alter cellular cholesterol metabolism resulting in pathological conditions. Filipin III is widely used as a probe for sterol localization in membranes. Interaction with cholesterol alters Filipin absorption and fluorescence spectra. This assay provides a simple, easy to perform, histochemical method of identification of unesterified cholesterol. BioVision charges an Ice pack fee for each order.

Catalog No. 50-111-9783


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