Chorionic Gonadotropin beta Chain (HCG beta) Mouse anti-Human, Clone: SPM529, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2343690.02MG
DescriptionChorionic Gonadotropin beta Chain (HCG beta) Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blotting.
|Chorionic Gonadotropin beta Chain (HCG beta)|
|Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml|
|CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB|
|Protein A purified|
|Store at 4C.|
|This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? and ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.|
|Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)|
|PBS with 0.05% BSA. with 0.05% Sodium Azide|
|Recombinant hCG beta protein|
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