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Chorionic Gonadotropin beta Chain (HCG beta) Mouse anti-Human, Clone: SPM529, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2343690.02MG

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Catalog No. NBP234369F


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Description

Description

Chorionic Gonadotropin beta Chain (HCG beta) Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blotting.
Specifications

Specifications

Chorionic Gonadotropin beta Chain (HCG beta)
SPM529
Western Blot 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
P01233
CGB3choriogonadotropin subunit beta, CGB5, CGB7, CGB8, CG-beta, Chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit, chorionic gonadotropin, beta polypeptide, hCGB
Mouse
IgG1
Protein A purified
RUO
Store at 4C.
Monoclonal
This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? and ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
Purified
CGB
Recombinant hCG beta protein
22 kDa
0.02 mg
Cancer
Primary
1082
Human
Documents
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