Invitrogen™ CHRM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595151

Catalog No. PIPA595151

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL.

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Specifications

• Antigen: CHRM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHRM1
• Gene Alias: acetylcholine receptor; acetylcholine receptor, muscarinic 1; AChR M1; cholinergic receptor; cholinergic receptor muscarinic 1; Cholinergic receptor, muscarin 1; cholinergic receptor, muscarinic 1; cholinergic receptor, muscarinic 1, CNS; CHRM1; Chrm-1; HM1; M1; M1 mAChR; m1 muscarinic acetylcholine receptor protein; M1R; MGC30125; muscarinic acetylcholine receptor M1; muscarinic receptor M1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1128, 12669, 25229
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P08482, P11229, P12657
• Gene Symbols: CHRM1
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human muscarinic Acetylcholine Receptor 1 (303-317aa KMPMVDPEAQAPTKQ).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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