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CHRNA3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549725

Catalog No. PA549725


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Description

Description

The antibody detects endogenous level of total CHRNA3 protein.

CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
Specifications

Specifications

CHRNA3
Polyclonal
Unconjugated
CHRNA3
Liquid
CHRNA3
Synthetic peptide corresponding to a region derived from 69-83 amino acids of Human cholinergic receptor, nicotinic, alpha 3 (neuronal)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Immunohistochemistry (Paraffin), Western Blot
1.2 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P32297, Q8R4G9, P04757
cholinergic receptor, nicotinic, alpha 3 (neuronal), LNCR2, PAOD2, NACHRA3
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
110834, 1136, 25101
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