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CHST6 Mouse anti-Canine, Human, Mouse, Non-human primate, Clone: OTI1D1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526461

Catalog No. PIMA526461


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Description

Description

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These enzymes differ in their tissue distributions and substrate specificities, although the gene structure (number and length of exons) is similar among family members. Carbohydrate sulfotransferase 5 (CHST5) (also referred to as GlcNAc6ST-3 or IGn6ST) and carbohydrate sulfotransferase 6 (CHST6) (also referred to as GlcNAc6ST-5 or Cgn6ST) are predomitly expressed in the intestine and cornea, respectively. They are highly homologous and both are orthologs of the murine CHST5. CHST5 and CHST6 may be the result of gene duplication. They catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. CHST5 preferably mediates the sulfation of short carbohydrates and O-linked sugars of mucin-type acceptors. CHST6 mediates the sulfation of keratan in the cornea, which is important in maintaining corneal transparency.
Specifications

Specifications

CHST6
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9GZX3
Carbohydrate sulfotransferase 6 (EC:2.8.2.-); Corneal N-acetylglucosamine-6-O-sulfotransferase; C-GlcNAc6ST; hCGn6ST; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta; GST4-beta; N-acetylglucosamine 6-O-sulfotransferase 5; GlcNAc6ST-5; Gn6st-5; CHST6
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
4166, 489707
Western Blot
OTI1D1
Unconjugated
CHST6
Liquid
CHST6, LOC489707
Human recombit protein fragment corresponding to amino acids 202-395 of CHST6 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human, Mouse, Non-human primate
Documents
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