CK1 gamma-1 Mouse anti-Human, Clone: OTI1D7, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526789
DescriptionCasein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKI alpha, gamma, epsilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2 beta2 or an alpha alpha ft. beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Casein kinase I isoform gamma-1, CKI-gamma 1, CSNK1G1, KC1G1, CK1G1, CKI gamma1, CK-I gamma1, CKI- gamma1, CKI gamma-1, CKI gamma1, CK I gamma1, CKI gamma1, CKI gamma 1, CKI gamma 1, CKI-gamma-1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 163-422 of CSNK1G1 produced in E.coli|
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