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CKAP4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 166861AP150UL

Encompass_Preferred

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Catalog No. 50-556-769


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Description

Description

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
Specifications

Specifications

CKAP4
Polyclonal
Unconjugated
CKAP4
63 kDa membrane protein, CKAP4, CLIMP 63, ERGIC 63, p63
Rabbit
Antigen Affinity Chromatography
RUO
10970, 216197, 362859
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q07065, Q8BMK4
Ckap4
CKAP4 Fusion Protein Ag10019
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
SDS
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