CKMT1A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 153461AP
DescriptionMitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many maligt cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|c, CKMiMi, CKMT, CKMT1, CKMT1A, Mia CK, U MtCK|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|CKMT1A Fusion Protein Ag7583|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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