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Cayman Chemical Cl-Amidine (hydrochloride), 1373232-26-8, 1 mg

Supplier: Cayman Chemical 105991

A pan PAD inhibitor (IC50s = 0.8, 6.2, and 5.9 µM for PAD1, PAD3, and PAD4, respectively, in vitro); irreversibly inactivates PAD4 (kinact/KI = 13,000 M-1min-1) and PAD3 (kinact/KI = 2,000 M-1min-1); cytotoxic to HL-60, MCF7, and HT-29 cancer cell lines (IC50s = 0.25, 0.05 and 1 μM, respectively),
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