Invitrogen™ Claudin 11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553027

Catalog No. PIPA553027

Description

Immunogen sequence: DAQAFGENRF YYTAGSSSPT HAKSAHV Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.

The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four trans-membrane domains and two extracellular loops, make up tight junction strands. Claudin-11 is an oligodendrocyte-specific protein that is expressed in the tight junctions of Sertoli cells and myelin sheaths in mice.

Specifications

• Antigen: Claudin 11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cldn11
• Gene Alias: claudin 11; claudin 11 (oligodendrocyte transmembrane protein); Claudin11; claudin-11; Cldn11; hypothetical protein LOC508268; oligodendrocyte transmembrane protein; Oligodendrocyte-specific protein; OSP; OTM
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5010
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75508
• Gene Symbols: Cldn11
• Immunogen: Recombinant protein corresponding to Human Claudin 11. Recombinant protein control fragment (Product #RP-90657).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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