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CLN2 Mouse anti-Human, Clone: 1C11-1A7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524560

Catalog No. PIMA524560


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Description

Description

Peptide Sequence: MPGRCQSDAA MRVNGPASRA PAGWTSGSLH TGPRAGRPRA QARGVRGRGL LLRPRPAKEL PLPRKGGAWA PAGNPGPLHP LGVAVGMAGS GRLVLRPWIR ELILGSETPS SPRAGQLLEV LQDAEAAVAG PSHAPDTSDV GATLLVSDGT HSVRCLVTRE ALDTSDWEEK EFGFRGTEGR LLLLQDCGVH VQVAEGGAPA EFYLQVDRFS LLPTEQPRLR VPGCNQDLDV QKKLYDCLEE HLSESTSSNA GLSLSQLLDE MREDQEHQGA LVCLAESCLT LEGPCTAPPV THWAASRCKA TGEAVYTVPS SMLCISENDQ LILSSLGPCQ RTQGPELPPP DPALQDLSLT LIASPPSSPS SSGTPALPGH MSSEESGTSI SLLPALSLAA PDPGQRSSSQ PSPAICSAPA TLTPRSPHAS RTPSSPLQSC TPSLSPRSHV PSPHQALVTR PQKPSLEFKE FVGLPCKNRP PFPRTGATRG AQEPCSVWEP PKRHRDGSAF QYEYEPPCTS LCARVQAARL PPQLMAWALH FLMDAQPGSE PTPM

This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Specifications

Specifications

CLN2
Monoclonal
Unconjugated
TPP1
Liquid
TPP1
ACD (AAH16904, 1 a.a. ∽ 544 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Protein A
RUO
Antibody
Monoclonal
Human
ELISA, Immunoprecipitation, Western Blot
1C11-1A7
PBS with no preservative; pH 7.4
O14773
GIG1, CLN2, LPIC, TPP-1, cell growth-inhibiting gene 1 protein, growth-inhibiting protein 1, lysosomal pepstatin insensitive protease, tripeptidyl aminopeptidase, tripeptidyl-peptidase 1
Mouse
IgG1, kappa
100 μg
-20° C
Primary
1200
Documents
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