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CLN3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 203861AP

Catalog No. 50-173-2861


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Description

Description

CLN3 is a highly glycosylated, hydrophobic, 438-amino acid protein with 6 transmembrane domains. The CLN3 protein localizes to the lysosomal membrane and plays a role in lysosomal function. It may act as a chaperone involved in the folding and unfolding of other proteins, namely subunit C of the ATP synthase complex. Mutations in the CLN3 gene cause Batten disease, a recessively inherited neurodegenerative disorder of childhood caused by lysosomal accumulation of hydrophobic material, mainly ATP synthase subunit C. Batten disease is the most common form of a group of disorders known as neuronal ceroid lipofuscinoses (NCLs). Symptoms of Batten disease include progressive loss of vision, seizures, and psychomotor disturbances.
Specifications

Specifications

CLN3
0.25 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q13286, Q61124
Batten disease protein, BATTENIN, BTS, CLN3, JNCL, Protein CLN3
Rabbit
IgG
150 μL
-20°C
Primary
1201, 12752, 293485
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CLN3
Liquid
CLN3
CLN3 Fusion Protein Ag14224
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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