Invitrogen™ CNGA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101516

Catalog No. PIPA5101516

Description

Antibody detects endogenous levels of total CNGA1.

The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CNGA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cnga1
• Gene Alias: cGMP-gated cation channel alpha-1; CNCG; CNCG1; cng channel; CNG channel alpha-1; CNG1; CNG-1; CNGA1; cyclic nucleotide gated channel alpha 1; cyclic nucleotide gated channel, cGMP gated; cyclic nucleotide-gated cation channel 1; Cyclic nucleotide-gated channel alpha-1; cyclic nucleotide-gated channel, photoreceptor; HCN; interleukin-1 homologue; RCNC1; RCNCa; RCNCalpha; Rod photoreceptor cGMP-gated channel subunit alpha; RP49
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1259, 12788, 85259
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P29973, P29974, Q62927
• Gene Symbols: Cnga1
• Immunogen: A synthesized peptide derived from human CNGA1(Accession P29973), corresponding to amino acid residues N404-L454.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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