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CNPase Mouse anti-Human, Clone: OTI3C3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527394

Catalog No. PIMA527394


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Description

Description

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. This gene may be associated with susceptibility to schizophrenia in a small portion of cases. An alternative splice variant has been described but its biological nature has not been determined.
Specifications

Specifications

CNPase
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P09543
CNP1, 2′, 3′ cyclic nucleotide 3′ phosphohydrolase; 2′,3′-cyclic-nucleotide 3′-phosphodiesterase; CNPase
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1267
Immunohistochemistry (Paraffin), Western Blot
OTI3C3
Unconjugated
CNP
Liquid
CNP
Full length human recombit protein of CNP produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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