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  6. CNQX, Tocris Bioscience™

CNQX, Tocris Bioscience™

Catalog Number 019010
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
115066-14-3
C9H4N4O4
232.155
RPXVIAFEQBNEAX-UHFFFAOYSA-N
cnqx, 6-cyano-7-nitroquinoxaline-2,3-dione, unii-6ote87sccw, 7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carbonitrile, 6ote87sccw, 3h cnqx, 6-cyano-2,3-dihydroxy-7-nitroquinoxaline, 1,4-dihydro-2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile, 6-quinoxalinecarbonitrile, 1,2,3,4-tetrahydro-7-nitro-2,3-dioxo, 2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile
3721046
CHEBI:34468
7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
C1=C(C(=CC2=C1NC(=O)C(=O)N2)[N+](=O)[O-])C#N
This item is not returnable. View return policy
115066-14-3
C9H4N4O4
232.155
RPXVIAFEQBNEAX-UHFFFAOYSA-N
cnqx, 6-cyano-7-nitroquinoxaline-2,3-dione, unii-6ote87sccw, 7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carbonitrile, 6ote87sccw, 3h cnqx, 6-cyano-2,3-dihydroxy-7-nitroquinoxaline, 1,4-dihydro-2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile, 6-quinoxalinecarbonitrile, 1,2,3,4-tetrahydro-7-nitro-2,3-dioxo, 2,3-dihydroxy-7-nitro-6-quinoxalinecarbonitrile
3721046
CHEBI:34468
7-nitro-2,3-dioxo-1,4-dihydroquinoxaline-6-carbonitrile
C1=C(C(=CC2=C1NC(=O)C(=O)N2)[N+](=O)[O-])C#N

Description

Potent and selective non-NMDA iGluR antagonist

CNQX is an AMPA and kainate receptor antagonist (IC50 values are 0.3 μM and 1.5 μM for AMPA and kainate receptors, respectively). CNQX is also an antagonist at the glycine modulatory site on the NMDA receptor complex (IC50 = 25 μM). CNQX can be used to isolate GABAA receptor-mediated spontaneous inhibitory postsynaptic currents and antagonizes non-NMDA receptor-mediated responses in cultured cerebellar granule cells. CNQX shows neuroprotective effects in models of ischemia and inhibits seizure-like activity in hippocampal neurons.

CNQX Disodium Salt (Cat. No. 1045) also available.

Quantity 10 mg
Formula Weight 232.16
Percent Purity >99%
Chemical Name or Material CNQX

Safety and Handling

Recommended Storage Store at Room Temperature
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