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Invitrogen™ CNTF Rat ELISA Kit Available on GSA/VA Contract for Federal Government customers only.

Sandwich ELISA Kit

$491.00


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Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
ERCNTF Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.
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Invitrogen™
ERCNTF
96 Tests
Each for $491.00
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Description

Description

The Rat Ciliary NeuroTrophic Factor (Rt CNTF) ELISA quantitates Rt CNTF in rat serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Rt CNTF. Principle of the method The Rat CNTF solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen. Rigorous validation Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.

CNTF (ciliary neurotrophic factor) is a polypeptide hormone with activity that is limited to the nervous system. It plays a role in neurotransmitter synthesis, membrane hyper polarization, and neuronal growth. CNTF promotes development of nervous system, and is involved in muscle morphogenesis. It also plays an important role in minimizing damage to neurons during inflammation. CNTF activates JAK-STAT, and PI3K signaling cascades. The protein is encoded by the gene CNTF located on chromosome 11.

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