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COL11A2 Mouse anti-Human, Clone: GT473, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527738

Catalog No. PIMA527738


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Description

Description

Positive Control: human COL11A2-transfected 293T cells (N-terminal fragment of COL11A2 isoform 1) Predicted Reactivity: Mouse (85%), Rat (85%), Bovine (93%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal domit non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.
Specifications

Specifications

COL11A2
Monoclonal
1 mg/mL
PBS with no preservative
P13942
COL11A2
Recombit protein encompassing a sequence within the N-terminus region of human COL11A2. The exact sequence is proprietary.
Protein G
RUO
Antibody
Monoclonal
Human
Immunocytochemistry, Immunofluorescence, Western Blot
GT473
Unconjugated
COL11A2
Liquid
Mouse
IgG2a
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
1302
Documents
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