COL3A1 Mouse anti-Human, Clone: OTI2G3, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA812161

Catalog No. 50-168-4431

Description

Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Specifications

• Antigen: COL3A1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P02461
• Gene Symbols: COL3A1
• Immunogen: Human recombit protein fragment corresponding to amino acids 981-1205 of human COL3A1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI2G3
• Conjugate: Unconjugated
• Gene: COL3A1
• Gene Alias: EDS4A, EDSVASC
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1281
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid