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Collagen II Ab-3 Mouse Monoclonal Antibody, Epredia™
Obtain accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Epredia™ Collagen II Ab-3, Mouse Monoclonal Antibody.
Supplier: Epredia MS306R7
Description
Host Species: Mouse
Clone: 6B3
Isotype: IgG1
Species Reactivity: Human, Mouse, Chicken and Salamander. Others not known.
Epitope: Triple helix of type II collagen
Immunogen: Purified type II collagen; obtained from the adult chicken sternum by limited pepsinization
Positive Control: Cartilage in lung or fetus
Cellular Localization: Cartilage matrix
In Western blotting, Ab-3 reacts with the TCA fragment of lathyritic type II collagen after digestion with mammalian collagenase. It also reacts with pepsin-digested type II collagen. Immunoblotting of CNBr peptides of collagen II shows that MAb 6B3 reacts with CB 11 fragment which is the site of immunogenic and arthritogenic epitopes along the intact type II molecule. In Western blotting (but not ELISA), Ab-3 recognizes alpha1(II) as well as alpha3(XI) chain both of which have identical primary structure.
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting (Not verified)
- Immunofluorescence
Note:
USA: RUO; Int'l: RUO
Specifications
Collagen II Ab-3 | |
Monoclonal | |
Unconjugated | |
Purified type II collagen; obtained from the adult chicken sternum by limited pepsinization | |
RUO | |
Primary | |
Prediluted |
Immunofluorescence, Immunohistochemistry (Paraffin) | |
6B3 | |
Mouse | |
7 mL | |
Extracellular Matrix | |
Chicken, Human, Mouse, Salamander | |
IgG1 |
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