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COPS6 Mouse anti-Human, Clone: OTI4E7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526223

Catalog No. PIMA526223


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Description

Description

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
Specifications

Specifications

COPS6
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q7L5N1
COP9 signalosome complex subunit 6; SGN6; Signalosome subunit 6; JAB1-containing signalosome subunit 6; MOV34 homolog; Vpr-interacting protein; hVIP; COPS6; CSN6, HVIP
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10980
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI4E7
Unconjugated
COPS6
Liquid
COPS6
Human recombit protein fragment corresponding to amino acids 58-327 of COPS6 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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