COPS6 Mouse anti-Human, Clone: OTI4E7, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526223
DescriptionThe protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|COP9 signalosome complex subunit 6; SGN6; Signalosome subunit 6; JAB1-containing signalosome subunit 6; MOV34 homolog; Vpr-interacting protein; hVIP; COPS6; CSN6, HVIP|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 58-327 of COPS6 produced in E.coli|
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