BioVision Inc COX-2 Inhibitor Screening Kit (Fluorometric): COX-2 Inhibitor Screening Kit (Fluorometric): Simple method to screen/study/characterize Cyclooxygenase-2 Inhibitors, includes COX-2 Inhibitor, Celecoxib. Convenient & Reliable. 100 Assays.
Manufacturer: BioVision Inc K547100
COX-2 Inhibitor Screening Kit (Fluorometric): Cyclooxygenase (COX), also known as prostaglandin-endoperoxide synthase (PTGS, EC 188.8.131.52), is an enzyme that is responsible for the formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane. There are two known isoenzymes: COX-1 and COX-2. COX-1 is constitutively expressed in many tissues and is the predominant form in gastric mucosa and in kidney. COX-2 is not expressed under normal conditions in most cells, but elevated levels are found during inflammation. Pharmacological inhibition of COX by non-steroidal anti-inflammatory drugs (NSAID) can provide relief from the symptoms of inflammation and pain. BioVision's COX-2 Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of COX-2 inhibitors. The assay is based on the fluorometric detection of Prostaglandin G2, the intermediate product generated by the COX enzyme.
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