COX2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA594950

Catalog No. PIPA594950

Description

Synthetic peptide sequence: 26-41aa, CQNRGVCMSVGFDQYK. Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

COX2 (Cyclooxygenase 2, PTGS2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged.

Specifications

• Antigen: COX2
• Classification: Polyclonal
• Formulation: 0.2mg sodium phosphate with 0.9MG NaCl, 0.9MG NaCl, 5MG BSA, 5MG BSA and 0.05MG sodium azide, 0.05MG sodium azide, 0.05MG thimerosal, 0.05MG thimerosal
• Gene Accession No.: P35354, P35355, Q05769
• Gene Symbols: Ptgs2
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human COX2, different from the related rat sequence by two amino acids.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: PTGS2
• Gene Alias: Prostaglandin G/H synthase 2; 1.14.99.1; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2; PTGS2; COX2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 19225, 29527, 5743
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized