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COX7A2L Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551292

Catalog No. PA551292


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Description

Description

The antibody detects endogenous levels of total COX7A2L protein.

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.
Specifications

Specifications

COX7A2L
Polyclonal
Unconjugated
COX7A2L
Liquid
COX7A2L
Synthetic peptide of human COX7A2L
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.9 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
O14548
COX7AR, COX7RP
Rabbit
IgG
100 μL
-20°C
Primary
9167
Documents
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