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  5. Tocris Bioscience™ CP 724714
  6. 597350

Tocris Bioscience™ CP 724714

Potent and selective ErbB2 inhibitor

Supplier:  Tocris Bioscience™ 5973/50

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Catalog No. 59-735-0

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.

This item is not returnable. View return policy

Description

Description

CP 724714 is a potent and selective ErbB2 inhibitor (IC50 = 10 nM). Exhibits 500-1000-fold selectivity for ErbB2 over ErbB1 and other related RTKs. Induces G1 cell cycle arrest in an ErbB2-overexpressing human cancer cell line. Promotes tumor apoptosis. Induces tumor regression in a human tumor xenograft model. Displays no apparent toxic effect on cardiac tissue.
Specifications

Specifications

2-Methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide
50 mg
C27H27N5O3
>98%
383432-38-0
EGF Receptor Inhibitors
469.53
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
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