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Tocris Bioscience™ CPI 613

PDH and KGDH inhibitor

$145.20 - $614.50


Chemical Name or Material 6,8-Bis[(phenylmethyl)thio]octanoic acid
Molecular Formula C22H28O2S2
CAS 95809-78-2
Product Type Target: Dehydrogenase Inhibitors
Formula Weight 388.59
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
53-481-0 View Documents Tocris Bioscience™
10mg Each for $145.20
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53-485-0 View Documents Tocris Bioscience™
50mg Each for $614.50
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Pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase (KGDH) inhibitor. Disrupts tumor cell mitochondrial metabolism, and increases mitochondrial reactive oxygen species (ROS) production in H460 lung carcinoma cells. Has no effect on KGDH activity in normal bronchial epithelial cells. Induces cell death of multiple tumor cell lines selectively over normal cells in vitro. Inhibits tumor growth of H460 and BxPC-3 tumor cell xenografts in mice.


6,8-Bis[(phenylmethyl)thio]octanoic acid
Target: Dehydrogenase Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

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