Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Tocris Bioscience™ CPI 613

PDH and KGDH inhibitor

$145.20 - $614.50

Specifications

Chemical Name or Material 6,8-Bis[(phenylmethyl)thio]octanoic acid
Molecular Formula C22H28O2S2
CAS 95809-78-2
Product Type Target: Dehydrogenase Inhibitors
Formula Weight 388.59
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
53-481-0 View Documents Tocris Bioscience™
5348/10
10mg Each for $145.20
Add to cart
 
53-485-0 View Documents Tocris Bioscience™
5348/50
50mg Each for $614.50
Add to cart
 
Description

Description

Pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase (KGDH) inhibitor. Disrupts tumor cell mitochondrial metabolism, and increases mitochondrial reactive oxygen species (ROS) production in H460 lung carcinoma cells. Has no effect on KGDH activity in normal bronchial epithelial cells. Induces cell death of multiple tumor cell lines selectively over normal cells in vitro. Inhibits tumor growth of H460 and BxPC-3 tumor cell xenografts in mice.
Specifications

Specifications

6,8-Bis[(phenylmethyl)thio]octanoic acid
95809-78-2
388.59
C22H28O2S2
Target: Dehydrogenase Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit