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Tocris™ CRID3 sodium salt

Potent NLRP3 inflammasome inhibitor; inhibits IL-1beta production

Manufacturer:  Tocris™ 5479/10

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Catalog No. 54-791-0


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Disclaimers:

For Research Use Only


Specifications

Description

Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production (IC50 = 7.5nM). Selective for NLRP3 inflammasome over NLRC4 inflammasome and Toll-like receptor signaling. Reduces severity of experimental autoimmune encephalomyelitis in mice. Also glutathione S-transferase omega 1 inhibitor. Orally bioavailable.
  • Chemical Name: N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt
  • Formula: C20H23N2NaO5S
  • CAS Number: 256373-96-3
  • Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
  • Purity: >97
Description & Specifications

Specifications

CRID3 sodium salt
>97
CRID3 sodium salt
426.46
10mg
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