Tocris™ CRID3 sodium salt

Potent NLRP3 inflammasome inhibitor; inhibits IL-1beta production

Manufacturer: Tocris™ 5479/10

 View more versions of this product

Catalog No. 54-791-0

  Check Availability
Add to Cart


For Research Use Only


    Description CRID3 sodium salt
    Quantity 10mg
    Product Type CRID3 sodium salt
    Molecular Weight 426.46
    Purity >97

    Potent NLRP3 inflammasome inhibitor; inhibits IL-1β production (IC50 = 7.5nM). Selective for NLRP3 inflammasome over NLRC4 inflammasome and Toll-like receptor signaling. Reduces severity of experimental autoimmune encephalomyelitis in mice. Also glutathione S-transferase omega 1 inhibitor. Orally bioavailable.

    • Chemical Name: N-[[(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino]carbonyl]-4-(1-hydroxy-1-methylethyl)-2-furansulfonamide sodium salt
    • Formula: C20H23N2NaO5S
    • CAS Number: 256373-96-3
    • Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
    • Purity: >97

  • Description & Specifications

Related Products

Product Content Feedback

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit