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CRYBB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 181541AP

Catalog No. 50-173-2019


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Description

Description

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts.
Specifications

Specifications

CRYBB2
0.4 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P43320, P62696, P62697
Beta B2 crystallin, Beta crystallin B2, Beta crystallin Bp, CCA2, CRYB2, CRYB2A, CRYBB2, crystallin, beta B2, D22S665
Rabbit
IgG
150 μL
-20°C
Primary
12961, 1415, 25422
Western Blot
Unconjugated
CRYBB2
Liquid
Crybb2
CRYBB2 Fusion Protein Ag12906
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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