CRYBB2 Mouse anti-Human, Mouse, Rat, Clone: 3H7, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524876
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts.
|Recombit full length Human CRYBB2 .|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.4|
|P43320, P62696, P62697|
|Beta crystallin B2;Beta crystallin Bp;Beta-B2 crystallin;CCA 2;CCA2;CRBB2_HUMAN;CRYB B2;CRYB2;CRYB2A;CRYBB 2;CRYBB2;Crystallin beta B2;D22S665; OTTHUMP00000198622;|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|12961, 1415, 25422|
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