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CRYBB2 Mouse anti-Human, Mouse, Rat, Clone: 3H7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524876

Catalog No. PIMA524876


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Description

Description

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts.
Specifications

Specifications

CRYBB2
Monoclonal
Unconjugated
CRYBB2
Liquid
CRYBB2
Recombit full length Human CRYBB2 .
Antigen affinity chromatography
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin), Western Blot
3H7
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P43320, P62696, P62697
Beta crystallin B2;Beta crystallin Bp;Beta-B2 crystallin;CCA 2;CCA2;CRBB2_HUMAN;CRYB B2;CRYB2;CRYB2A;CRYBB 2;CRYBB2;Crystallin beta B2;D22S665; OTTHUMP00000198622;
Mouse
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
12961, 1415, 25422
Documents
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