Tocris™ Cryptotanshinone

STAT3 inhibitor. Also displays multiple other activities

Manufacturer: Tocris™ 3713/10

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Catalog No. 37-131-0R

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Disclaimers:

For Research Use Only


    Specifications

    Product Type Cryptotanshinone
    Inhibitors Cryptotanshinone
    Purity >98
    Molecular Weight 296.36
    Quantity 10mg

    Major tanshinone isolated from Salvia miltiorrhiza that exhibits multiple activities. Exhibits antitumor activity via inhibition STAT3 activity (IC50 = 4.6µM). Displays antibacterial and anti-inflammatory activity and acts as an antidiabetes and antiobesity agent via activation of AMP-activated protein kinase (AMPK). Also improves cognitive impairment in Alzheimer's disease transgenic mice by inhibition of acetylcholinesterase (IC50 = 4.09µM) and reduction in Aβ peptide generation.

    • Chemical Name: 1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl[1,2-b]furan-10,11-dione
    • Formula: C19H20O3
    • CAS Number: 35825-57-1
    • Solubility: Soluble to 10mM in DMSO
    • Purity: >98

  • Description & Specifications

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