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CSH1 Mouse anti-Human, Clone: OTI4D6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526276

Catalog No. PIMA526276


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Description

Description

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.
Specifications

Specifications

CSH1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P0DML2
hPL, CS-1, CSA, CSMT, PL, hCS-A, choriomammotropin, chorionic somatomammotropin A, chorionic somatomammotropin hormone, placental lactogen
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1442
Immunocytochemistry, Immunofluorescence, Western Blot
OTI4D6
Unconjugated
CSH1
Liquid
CSH1
Full length human recombit protein of CSH1 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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