Invitrogen™ CSH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529998

Catalog No. PIPA529998

Description

Recommended positive controls: A549, H1299, HCT116, MCF-7. Predicted reactivity: Chimpanzee (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity.

Specifications

• Antigen: CSH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CSH2
• Gene Alias: Choriomammotropin; chorionic somatomammotropin B; chorionic somatomammotropin hormone 2; CS-2; CSB; CSH2; GHB1; growth hormone B1; hCS-B; Lactogen; PL; Placental lactogen
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1443
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P0DML3
• Gene Symbols: CSH2
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 217 of Human CSH2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG