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CTLA-4 Hamster anti-Mouse, Janelia Fluor 646, Clone: 1B8, Novus Biologicals™

Hamster Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP141000JF646

Catalog No. NBP14000646


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Description

Description

CTLA-4 Monoclonal antibody specifically detects CTLA-4 in Mouse samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
Specifications

Specifications

CTLA-4
1B8
Flow Cytometry, Immunocytochemistry/Immunofluorescence
Purified
CTLA4
Extracellular portion of mouse CD152 fused to a mouse IgG2a.
Protein G purified
Signal Transduction
Primary
1493
Mouse
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Janelia Fluor 646
50mM Sodium Borate with 0.05% Sodium Azide
CD, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Hamster
IgG
0.1mL
Store at 4°C in the dark.
Monoclonal
This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.
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