CTLA-4 Hamster anti-Mouse, Janelia Fluor 646, Clone: 1B8, Novus Biologicals™
Hamster Monoclonal Antibody
Manufacturer: Novus Biologicals NBP141000JF646
DescriptionCTLA-4 Monoclonal antibody specifically detects CTLA-4 in Mouse samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
|Flow Cytometry, Immunocytochemistry/Immunofluorescence|
|Extracellular portion of mouse CD152 fused to a mouse IgG2a.|
|Protein G purified|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence|
|Janelia Fluor 646|
|50mM Sodium Borate with 0.05% Sodium Azide|
|CD, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4|
|Store at 4°C in the dark.|
|This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.|
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