CTNNB1 Rabbit anti-Human, Polyclonal , Abnova™
Rabbit polyclonal antibody raised against recombinant human CTNNB1.
Manufacturer: Abnova Corporation PAB29423
Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the 'contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete.[supplied by OMIM]Sequence: SEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPD
|Immunohistochemistry (1:200-1:500) Immunofluorescence (1-4 ug/mL) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human CTNNB1.|
|Antigen affinity purification|
|Immunofluorescence, Immunohistochemistry (PFA fixed)|
|Rabbit polyclonal antibody raised against recombinant human CTNNB1.|
|In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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