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CTP synthase Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 159141AP150UL

Encompass_Preferred

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Catalog No. 50-173-0571


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Description

Description

There are two genes encoding members of a new family of type II integral membrane proteins. Both are ubiquitously expressed, and tissue-specific alternative mRNA initiation and splicing generate at least two major isoforms of each protein, with the smaller isoforms being truncated at the N-terminus. These proteins are called nesprin-l and -2 for nuclear _envelope _spectrin repeat, as they are characterized by the presence of multiple, clustered spectrin repeats, bipartite nuclear localization sequences and a conserved C-terminal, single transmembrane domain. Transient transfection of EGFP-fusion expression constructs demonstrated their localization to the nuclear membrane with a novel C-terminal, TM-domain-containing sequence essential for perinuclear localization. Nesprin-l is developmentally regulated in both smooth and skeletal muscle and is relocalized from the nuclear envelope to the nucleus and cytoplasm during C2Cl2 myoblast differentiation. Nesprins may function as ′dystrophins of the nucleus′ to maintain nuclear organization and structura integrity
Specifications

Specifications

CTP synthase
Polyclonal
Unconjugated
CTPS1
CTP synthase, CTP synthase 1, CTP synthetase 1, CTPS, CTPS 1, CTPS1, UTP ammonia ligase 1
Rabbit
Antigen Affinity Chromatography
RUO
1503, 313560, 51797
-20°C
Liquid
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
0.16 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P17812, P70698
Ctps, Ctps1
CTP synthase Fusion Protein Ag8707
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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