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CUEDC2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 201231AP

Catalog No. 50-173-2714


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Description

Description

The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, approximately 40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-alpha and IKK-beta and decrease the activation of NF-kappa-B by decreasing the activation of IKK.
Specifications

Specifications

CUEDC2
0.35 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9CXX9, Q9H467
C10orf66, CUE domain containing 2, CUEDC2
Rabbit
IgG
150 μL
-20°C
Primary
67116, 79004
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
CUEDC2
Liquid
CUEDC2
CUEDC2 Fusion Protein Ag13847
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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