Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000372593

Medchemexpress LLC CWI1-2 | 2408590-36-1 | C22H17Cl3N6O3 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1532745MG

Encompass_Preferred

CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts. It induces apoptosis and differentiation, and demonstrates promising anti-leukemic effects.

  • Binds to IGF2BP2
  • Inhibits interaction with m6A-modified target transcripts
  • Induces apoptosis and differentiation
  • Shows promising anti-leukemic effects
  • Exhibits antiproliferative activity with an IC50 of 200 nM against human THP-1 cells
  • Reduces glutamine uptake and impairs mitochondrial function in AML cells
  • Significantly inhibits the colony-forming ability of leukemic mouse blasts
  • Greatly impairs the self-renewal of leukemic stem/initiating cells

Catalog No. 50-003-72593


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.