Cyclin D1 Mouse anti-Human, Mouse, Rat, Primate, Alexa Fluor 350, Clone: DCS-6, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233138AF350
DescriptionCyclin D1 Monoclonal antibody specifically detects Cyclin D1 in Human,Mouse,Rat,Primate samples. It is validated for ELISA.
|B-cell lymphoma 1 protein, BCL-1, BCL-1 oncogene, BCL1D11S287E, cyclin D1, cyclin D1 (PRAD1: parathyroid adenomatosis 1), G1/S-specific cyclin D1, G1/S-specific cyclin-D1, PRAD1 oncogene, PRAD1B-cell CLL/lymphoma 1, U21B31|
|Store at 4°C in the dark.|
|Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.|
|Alexa Fluor™ 350|
|50 mM sodium borate with 0.05% sodium azide|
|Human recombinant full length Cyclin D1 protein was used as immunogen to generate this antibody.|
|Human, Mouse, Primate, Rat|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok