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Thermo Scientific™ Lab Vision™ Cyclin E Ab-5, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry and immunoprecipitation experiments with Thermo Scientific™ Cyclin E Ab-5, Mouse Monoclonal Antibody.

Specifications

Antigen Cyclin E Ab-5
Clone 13A3
Applications Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Conjugate Unconjugated
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Products 5
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
MS1060R1
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Thermo Scientific™
MS1060R1
1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS1060R7
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Thermo Scientific™
MS1060R7
7mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS1060S
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Thermo Scientific™
MS1060S
1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS1060S0
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Thermo Scientific™
MS1060S0
100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS1060S1
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Thermo Scientific™
MS1060S1
500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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Description

Description

Obtain accurate, reproducible results in immunohistochemistry and immunoprecipitation experiments with Thermo Scientific™ Cyclin E Ab-5, Mouse Monoclonal Antibody.

Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Host Species: Mouse

Clone: 13A3

Isotype: IgG2a/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human cyclin E protein

Molecular Weight: Doublet of 50 kDa and a single band of 42 kDa

Positive Control: SKBR3 and LS174T cells; Breast CA or placenta

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunoprecipitation (Native and Denatured)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Cyclin E Ab-5
Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
RUO
Primary
IgG2a kappa
13A3
Monoclonal
Murine
Cell Cycle
Recombinant human cyclin E protein
SDS
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